1. What is lamotrigine (Lamictal)?
Lamotrigine is an anticonvulsant that is chemically unrelated to any other anticonvulsant or mood regulating medication.
2. When was lamotrigine approved for marketing in the USA and for what indications may it be promoted?
Lamotrigine received final approval for marketing in the USA on 27 December 1994 and was labeled for use as an anticonvulsant. In 2003 it was approved by the FDA for use as a treatment for people with bipolar disorder.
3. Is a generic version of lamotrigine available?
Generic lamotrigine is available in the USA. There are a number of manufacturers. While most generic versions are generally effective, many individuals taking the generic manufactured by TEVA have found it to be unsatisfactory when they were forced to take it by their insurnace companies.
4. How does lamotrigine differ from other mood stabilizing drugs?
Lamotrigine differs from other mood stabilizing drugs in two major ways
1. Lamotrigine's frequent effectiveness for patients who have failed to respond to antidepressants or mood stabilizers;
2. Lamotrigine's relatively benign side-effect profile.
5. What, if anything, uniquely distinguishes lamotrigine from carbamazepine and valproate?
Lamotrigine has been successful in controlling rapid cycling and mixed bipolar states in people who have not received adequate relief from lithium, carbamazepine and/or valproate. It also appears that lamotrigine has significantly more antidepressant potency than either carbamazepine or valproate.
Lamotrigine is also useful as part of the treatment of some people with major (unipolar) depression.
Lamotrigine has recently been reported to be a useful treatment for some people with post-traumatic stress disorder (PTSD) and/or borderline personality disorder (BPD).
6. People with what sorts of psychiatric disorders are candidates for treatment with lamotrigine?
It is too early to be very specific about which mood disorders are most likely to respond to treatment with lamotrigine. Patients with hard-to-treat bipolar syndromes and with schizoaffective disorder have been treated more often than patients with "treatment-resistant" unipolar disorders. Some people with such hard to treat unipolar depressions have been treated with good results. Some patients diagnosed with Borderline Personality Disorder, a disorder that many psychiatrists believe is a variant of Bipolar Disorder, have responded to treatment with lamotrigine. Patients with Post-Traumatic Stress Disorder and with Depersonalization Disorder have also responded well to lamotrigine therapy.
7. Is lamotrigine useful for the treatment of acute depressed, manic and mixed states, and can it also be used to prevent future episodes of mania and/or depression?
The initial use of lamotrigine was to treat people with depressed, manic and mixed states that did not respond to existing medications. Some patients are now being maintained on lamotrigine on a long term basis in an attempt to prevent future episodes. Evidence regarding the effectiveness of lamotrigine as a long-term prophylactic agent is increasing.
8. Are there any laboratory tests that should precede the start of lamotrigine therapy?
Before lamotrigine is prescribed the patient should have a thorough medical evaluation, including blood and urine tests, to rule out any medical condition, such as thyroid disorders, that may cause or exacerbate a mood disorder.
9. How is treatment with lamotrigine initiated?
In people not taking carbamazepine or valproate, lamotrigine is usually initially prescribed at an initial dose of 12.5 or 25 mg a day and the dose increased by 12.5 or 25 mg every week or two.
In people taking valproate the initial dose of lamotrigine is often 12.5 mg/day and the drug is increased by 12.5 mg every ten days or two weeks.
In people taking carbamazepine somewhat larger initial doses and more rapid increases in dose are possible.
10. Are there any special problems prescribing lamotrigine for people taking lithium, Tegretol, or Depakote?
An interaction between lithium and lamotrigine has not been reported.
Carbamazepine induced enzymes that facilitate the metabolism of lamotrigine. Because of that, blood levels of lamotrigine are somewhat lower in people taking carbamazepine than in those not taking carbamazepine.
Valproate has the ability to double plasma levels of lamotrigine. Because of that, when lamotrigine is started in people taking valproate, the initial dose should be approximately one-half as much as is usually initially prescribed.
11. What is the usual final dose of lamotrigine?
When used as an antidepressant or as a mood-stabilizing agent the final dose of lamotrigine is most often between 100 and 200 mg/day. Some people require doses as high as 600 mg/day to achieve a good antidepressant effect. Such doses should be avoided in patients taking valproate because of the pharmacokinetic effect of valproate that increases plasma levels of lamotrigine, and the accompanying increased risk of serious dermatological side effects.
12. How long does it take for lamotrigine to 'kick-in?'
While some people notice the antimanic and antidepressant effects early in treatment, others have to take a therapeutic amount of lamotrigine for up to a month before being aware of a significant amount of improvement.
13. What are the side-effects of lamotrigine?
Here is a listing of lamotrigine's side effects that affected 10% or more of the 711 people taking the drug during clinical trials and the frequency of those side effects in the 419 people treated with placebo in those trials
Adverse Reactions (%)
Adverse Reaction Lamotrigine Placebo
Dizziness 38 13
Headache 29 19
Double Vision 28 7
Unsteadiness 22 6
Nausea 19 10
Blurred Vision 16 5
Sleepiness 14 7
Rash 10 5
Vomiting 10 4
Side-effects are most noticeable the few days after an increase in dose and then usually fade.
14. Which side-effects are severe enough to force people to discontinue lamotrigine? Are sexual side-effects a problem?
The side-effect of lamotrigine that most often causes the drug to be discontinued is a rash. Rashes can be mild, similar to a slight sunburn, or can be quite severe resembling a severe case of poison-ivy. The more severe the rash the less likely it is that the individual will be able to continue the medication. ALL rashes should be immediately reported to the physicians prescribing the lamotrigine.
About one in ten people taking lamotrigine develops a mild rash and about 1 in a thousand develop a severe rash requiring treatment. Many people with a mild rash can continue to take lamotrigine, sometimes together with an antihistamine.
A rash is more likely to develop when the initial doses of lamotrigine are high or when lamotrigine is too rapidly started when someone is taking valproate.
It is important that people taking lamotrigine who develop a rash immediately contact their physician as there have been a few deaths in people who have developed lamotrigine-induced rashes (Stevens-Johnson syndrome).
Sexual side-effects are not a problem with lamotrigine.
15. Does lamotrigine have any psychiatric side effects?
Among the rarely reported side effects of lamotrigine are agitation, anxiety, concentration problems, confusion, depression, emotional instability, irritability, and mania.
Mania or hypomanic induced by lamotrigine responds well to treatment with lithium or small doses of topiramate.
16. How does lamotrigine interact with prescription and over-the-counter medications?
Only a few interactions between lamotrigine and other drugs have been identified. Lamotrigine increases the plasma level of carbamazepine and its metabolites. Carbamazepine lowers the concentration of lamotrigine in the blood.
Valproate doubles the plasma level of lamotrigine, and the level of valproate is decreased by about 25% in people taking lamotrigine.
Phenobarbital and primidone lower the plasma level of lamotrigine by about 40%.
Oral contraceptives can lower the plasma level of lamotrigine by as much as 50%.
Interactions with other prescription and over-the-counter drugs are not known at this time.
17. Is there an interaction between lamotrigine and alcohol?
Alcohol may increase the severity of the side-effects of lamotrigine.
18. Is lamotrigine safe for a woman who is about to become pregnant, pregnant or nursing an infant?
Lamotrigine is has been placed in the FDA pregnancy Category C
"Animal studies have shown an adverse effect on the fetus but there are no adequate studies in humans; The benefits from the use of the drug in pregnant women may be acceptable despite its potential risks . . . ."
An increasing number of women with epilepsy are continuing lamotrigine throughout their pregnancies. Research on the effects of lamotrigine on their children is underway.
19. Is lamotrigine safe for children and adolescents?
While lamotrigine has been used with children and young adolescents in other countries. In the USA, because of the increased risk of fatal side-effects in the young, lamotrigine is only approved for use in those over the age of 16.
20. Can lamotrigine be used in elderly people?
Older people seem to handle lamotrigine similarly to younger ones. There is little experience using lamotrigine for the treatment of psychiatric disorders in the elderly.
21. Do symptoms develop if lamotrigine is suddenly discontinued?
There are no specific symptoms that have been described following the abrupt discontinuation of lamotrigine, other than the seizures that sometimes follow the rapid discontinuation of any anticonvulsant. Only when necessary because of a serious side effect, should lamotrigine be suddenly discontinued.
22. Is lamotrigine toxic if taken in overdose?
Data on overdoses are scarce. Two individuals who took over 4,000 mg of lamotrigine survived without long-lasting effects.
23. Can lamotrigine be taken along with MAO inhibitors?
Yes, the combination has been used without any special problems.
24. What does lamotrigine cost?
As of 4 April 2011, the per tablet cost of Lamictal brand lamotrigine, when ordered in lots of 100 tablets from a well-known mail-order pharmacy (Drugstore.com) was:
25 mg - $4.83
100 mg - $5.43
150 mg - $5.93
200 mg - $6.67 The per tablet cost of generic lamotrigine is:
25 mg - $0.30
100 mg - $0.30
150 mg - $0.53
200 mg - $0.53
25. Might lamotrigine be effective in people who have failed to receive benefit from other psychopharmacologic agents?
The major psychiatric use of lamotrigine is with people who have mood disorders that have not been adequately controlled by other medications.
26. What are the advantages of lamotrigine?
Lamotrigine seems to be effective in about two-thirds of people with bipolar mood disorders that have not responded to lithium or other mood-stabilizers. Some people who have not been able to tolerate any antidepressant because of switches to mania or increased speed or intensity of cycling, or because of the development of mixed states, have been able to tolerate therapeutic doses of anti- depressants when taking lamotrigine.
For most people, lamotrigine has minimal side effects and can be taken once a day.
Lamotrigine is also useful as a potentiating agent for antidepressants being used to treat people with major (unipolar) depression.
27. What are the disadvantages of lamotrigine?
As lamotrigine has only been available for a relatively short time, it was first marketed in 1990, there is no information about long term side-effects. As its use with people with mood disorders started even more recently, it is not known if people who initially do well on lamotrigine continue to do so after many years of treatment.
As with other medications with antidepressant activity, lamotrigine occasionally causes people to become hypomanic or manic. This can usally be controlled by small doses of lithium or topiramate.
There is a small chance of a serious, and in some cases life-threatening, rash developing in people taking lamotrigine. This side effect is more frequently seen in those under the age of 16 than in older persons.
28. Why should physicians prescribe, and patients take, lamotrigine, when there are mood regulating medications that have been available for many years?
There are two major reasons why physicians prescribe and patients take lamotrigine rather than older medications. They are that not everyone benefits from treatment with the older, better known drugs, and that some people find the side effects of the older drugs to be unacceptable.
29. Is lamotrigine available in countries other than the USA?
Lamotrigine is currently available in about 60 countries.
30. Where might one read in detail about lamotrigine and its use in treating people with mood disorders?
The most authoritative places to read about the psychiatric uses of lamotrigine are:
Treatment of Bipolar Illness: A Casebook for Clinicians and Patients
Handbook of Diagnosis and Treatment of Bipolar Disorders
Depression and Bipolar Disorder: Stahl's Essential Psychopharmacology, 3rd edition
100 mg - $5.43
150 mg - $5.93
200 mg - $6.67
100 mg - $0.30
150 mg - $0.53
200 mg - $0.53
This is an index of reports of adverse events (side effects, adverse reactions, etc.) related to Lamictal (Lamotrigine). Click on the relevant link below to view a selection of reports according to the event's seriousness level and/or the nature of the side effect / adverse reaction. Or scroll down to view a sample of recent reports further on this page.
Our database includes reports primarily from April 2009 to March 2010. The information is not vetted and should not be cosidered as verified clinical evidence.
All cases (1212)Our database includes reports primarily from April 2009 to March 2010. The information is not vetted and should not be cosidered as verified clinical evidence.
| Rash (170), Pyrexia (156), Convulsion (150), more >> |
Cases resulting in a serious event (1082)
| Pyrexia (153), Rash (146), Convulsion (141), more >> |
Cases resulting in death (62)
| Renal Failure (10), Pyrexia (9), Dyspnoea (6), more >> |
Cases resulting in life threatening events (103)
| Pyrexia (22), Stevens-Johnson Syndrome (21), Rash (20), more >> |
Cases resulting in hospitalization (491)
| Pyrexia (131), Rash (110), Drug Rash With Eosinophilia and Systemic Symptoms (48), more >> |
Cases resulting in disability (72)
| Rash (12), Stevens-Johnson Syndrome (9), Balance Disorder (8), more >> |
Cases resulting in other serious reactions (555)
| Convulsion (99), Drug Exposure During Pregnancy (58), Rash (51), more >> |
Below is a sample of reports where side effects / adverse reactions may be related to Lamictal (Lamotrigine). For a complete list and/or a specific selection of reports, please use the links in the index above.
Possible Lamictal side effects / adverse reactions in 16 year old female
Reported by a consumer/non-health professional from United States on 2010-03-30Patient: 16 year old female, weighing 59.0 kg (129.7 pounds)
Reactions: Brain Injury, Educational Problem, Amnesia
Suspect drug(s):
Lamictal
Possible Lamictal side effects / adverse reactions in male
Reported by a individual with unspecified qualification from Italy on 2010-03-30Patient: male
Reactions: Thrombocytopenia, Stevens-Johnson Syndrome
Adverse event resulted in: hospitalization
Suspect drug(s):
Keppra
Dosage: 2 g oral
Administration route: Oral
Indication: Epilepsy
Start date: 2008-01-01
End date: 2010-03-02
Lamictal
Dosage: (40 mg oral)
Administration route: Oral
Indication: Epilepsy
Start date: 2010-02-05
End date: 2010-02-23
Depakin (Depkin)
Dosage: 500 mg bid oral
Administration route: Oral
Indication: Epilepsy
Start date: 2000-01-01
End date: 2010-03-02
Possible Lamictal side effects / adverse reactions in 23 year old female
Reported by a consumer/non-health professional from United States on 2010-03-29Patient: 23 year old female, weighing 61.2 kg (134.7 pounds)
Reactions: Grand MAL Convulsion, Drug Interaction, Mobility Decreased
Suspect drug(s):
Implanon
Dosage: 1 df;
Indication: Contraception
Start date: 2010-02-05
Lamictal
Indication: Drug USE FOR Unknown Indication
Other drugs received by patient: Topamax
Possible Lamictal side effects / adverse reactions in 26 year old male
Reported by a physician from United States on 2010-03-26Patient: 26 year old male, weighing 81.6 kg (179.6 pounds)
Reactions: Cognitive Disorder, Headache, Convulsion, Suicidal Ideation, Product Label Issue, Arthralgia, Alopecia, Dizziness, Unevaluable Event
Adverse event resulted in: life threatening event
Suspect drug(s):
Lamictal
Dosage: 100mg daily po
Administration route: Oral
Indication: Bipolar Disorder
Start date: 2010-02-15
End date: 2010-03-15
Lamictal CD
Dosage: 50mg daily po
Administration route: Oral
Start date: 2010-03-16
End date: 2010-03-20
Possible Lamictal side effects / adverse reactions in 26 year old female
Reported by a consumer/non-health professional from United States on 2010-03-24Patient: 26 year old female, weighing 63.5 kg (139.7 pounds)
Reactions: Palpitations, Dizziness, Drug Interaction, Fall, Tremor
Adverse event resulted in: hospitalization
Suspect drug(s):
Lamictal
Dosage: 2 200 mg pills 2 times per day po
Administration route: Oral
Indication: Epilepsy
Start date: 2007-01-01
End date: 2010-03-19
5 Hour Energy 2 OZ Living Essentials
Dosage: 1 bottle 1 time po
Administration route: Oral
Start date: 2010-03-18
End date: 2010-03-18
Possible Lamictal side effects / adverse reactions in 9 year old male
Reported by a physician from United States on 2010-03-24Patient: 9 year old male, weighing 117.0 kg (257.5 pounds)
Reactions: Drug Ineffective, Convulsion
Suspect drug(s):
Lamictal
Dosage: 200mg 2 bid ; 25mg 2 bid
Indication: Convulsion
Start date: 2005-01-01
Lamictal
Dosage: 200mg 2 bid ; 25mg 2 bid
Indication: Partial Seizures
Start date: 2005-01-01
Possible Lamictal side effects / adverse reactions in 34 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2010-03-18Patient: 34 year old female
Reactions: Nausea, Fall, Convulsion, Suicidal Ideation, Anxiety, Overdose, Visual Impairment, Petit MAL Epilepsy
Suspect drug(s):
Lexapro
Dosage: (10 mg), oral; (30 mg), oral
Administration route: Oral
Lamictal
Dosage: (1 in 1 d), oral; (100 mg), oral; (200 mg), oral; (475 mg), oral; (500 mg), oral
Administration route: Oral
Indication: Convulsion
End date: 2004-01-01
Lamictal
Dosage: (1 in 1 d), oral; (100 mg), oral; (200 mg), oral; (475 mg), oral; (500 mg), oral
Administration route: Oral
Indication: Convulsion
End date: 2009-11-30
Lamictal
Dosage: (1 in 1 d), oral; (100 mg), oral; (200 mg), oral; (475 mg), oral; (500 mg), oral
Administration route: Oral
Indication: Convulsion
Start date: 2001-01-01
Lamictal
Dosage: (1 in 1 d), oral; (100 mg), oral; (200 mg), oral; (475 mg), oral; (500 mg), oral
Administration route: Oral
Indication: Convulsion
Start date: 2009-12-01
Keppra
Dosage: oral; (3000 mg), oral
Administration route: Oral
Indication: Convulsion
Start date: 2004-01-01
Possible Lamictal side effects / adverse reactions in male
Reported by a physician from Germany on 2010-03-12Patient: male, weighing 56.0 kg (123.2 pounds)
Reactions: LIP Swelling, Pruritus, Angioedema, Rash Generalised, Blood Lactate Dehydrogenase Increased, Obesity, Urticaria Chronic
Adverse event resulted in: hospitalization
Suspect drug(s):
Lamictal
Other drugs received by patient: Keppra
Possible Lamictal side effects / adverse reactions in 59 year old male
Reported by a consumer/non-health professional from United States on 2010-03-12Patient: 59 year old male
Reactions: Weight Decreased, Productive Cough, Skin Exfoliation, Abasia, Pain, Malaise, Skin Ulcer, Skin Lesion, Oedema Mucosal, Rash Vesicular, Stevens-Johnson Syndrome, Stomatitis, Pneumonia, Increased Viscosity of Bronchial Secretion, Toxic Epidermal Necrolysis, Rash, Eating Disorder, Mucosal Erosion, Mucosal Inflammation, Burning Sensation, Disturbance in Attention, Eye Swelling, Immune System Disorder
Adverse event resulted in: hospitalization
Suspect drug(s):
Lamictal
Other drugs received by patient: Prozac; Concerta
Possible Lamictal side effects / adverse reactions in male
Reported by a consumer/non-health professional from United States on 2010-03-12Patient: male
Reactions: Therapeutic Response Decreased, Convulsion
Suspect drug(s):
Lamictal
Dosage: 300mg twice per day
Administration route: Oral
Topamax
Dosage: 400mg unknown
Administration route: Oral
Possible Lamictal side effects / adverse reactions in 20 year old female
Reported by a physician from Italy on 2010-03-12Patient: 20 year old female
Reactions: Jaundice, Blood Bilirubin Increased, Alanine Aminotransferase Increased, Hepatitis, Abdominal Pain Upper, Eosinophilia, Blood Amylase Increased, Gamma-Glutamyltransferase Increased, Aspartate Aminotransferase Increased
Adverse event resulted in: hospitalization
Suspect drug(s):
Lamictal
Possible Lamictal side effects / adverse reactions in
Reported by a pharmacist from Canada on 2010-03-11Patient:
Reactions: Drug Exposure During Pregnancy, Aniridia
Suspect drug(s):
Lamictal
Possible Lamictal side effects / adverse reactions in female
Reported by a pharmacist from United Kingdom on 2010-03-11Patient: female
Reactions: Ivth Nerve Paralysis
Suspect drug(s):
Lamictal
Possible Lamictal side effects / adverse reactions in 14 year old female
Reported by a consumer/non-health professional from United States on 2010-03-11Patient: 14 year old female
Reactions: Fatigue, Convulsion
Suspect drug(s):
Lamictal
Other drugs received by patient: Keppra
Possible Lamictal side effects / adverse reactions in female
Reported by a consumer/non-health professional from United States on 2010-03-11Patient: female, weighing 65.8 kg (144.7 pounds)
Reactions: Apparent Death, Suicidal Behaviour, Dizziness, Vision Blurred, Withdrawal Syndrome, Fall
Adverse event resulted in: life threatening event, hospitalization
Suspect drug(s):
Lamictal
Dosage: 5 mg sid oral 100 mg sid oral
Administration route: Oral
Indication: Depression
Start date: 2009-10-01
Lamictal
Dosage: 5 mg sid oral 100 mg sid oral
Administration route: Oral
Indication: Depression
Start date: 2009-11-01
Lamictal
Dosage: 5 mg sid oral 100 mg sid oral
Administration route: Oral
Indication: Depression
Start date: 2009-12-01
Other drugs received by patient: Cymbalta; Depakote
Possible Lamictal side effects / adverse reactions in female
Reported by a physician from Japan on 2010-03-11Patient: female
Reactions: Drug Eruption, Blood Urea Increased, Neutrophil Count Increased, Blood Lactate Dehydrogenase Increased, Platelet Count Increased, Blood Potassium Increased, Pyrexia, Protein Total Decreased, C-Reactive Protein Increased, Gamma-Glutamyltransferase Increased, Skin Lesion, Blood Creatinine Increased, Blood Sodium Decreased, White Blood Cell Count Increased, Lymphocyte Count Decreased
Adverse event resulted in: hospitalization
Suspect drug(s):
Lamictal
Other drugs received by patient: Seroquel; Depas; Rohypnol; Valerian
Possible Lamictal side effects / adverse reactions in female
Reported by a consumer/non-health professional from United States on 2010-03-11Patient: female
Reactions: Product Quality Issue, Choking, Drug Administration Error, Amnesia
Suspect drug(s):
Lamictal
Other drugs received by patient: Vitamin TAB
Possible Lamictal side effects / adverse reactions in 60 year old female
Reported by a physician from Switzerland on 2010-03-11Patient: 60 year old female
Reactions: Toxic Encephalopathy, Dementia, Encephalopathy, Fall
Adverse event resulted in: hospitalization
Suspect drug(s):
Remeron
Dosage: 45 mg;qd;po
Administration route: Oral
Indication: Depression
Valproate Sodium
Dosage: 300 mg; po
Administration route: Oral
Indication: Epilepsy
Lamictal
Dosage: 100 mg; bid; po
Administration route: Oral
Indication: Epilepsy
Trazodone HCL
Dosage: 50 mg;qd;po
Administration route: Oral
Indication: Depression
Possible Lamictal side effects / adverse reactions in 12 year old female
Reported by a pharmacist from Japan on 2010-03-11Patient: 12 year old female
Reactions: Hypoglycaemia, Coma
Adverse event resulted in: hospitalization
Suspect drug(s):
Lamictal
Other drugs received by patient: Depakene; Tegretol
Possible Lamictal side effects / adverse reactions in male
Reported by a consumer/non-health professional from United States on 2010-03-05Patient: male
Reactions: Depression Suicidal, Suicidal Ideation
Adverse event resulted in: hospitalization
Suspect drug(s):
Lamictal
Indication: Drug USE FOR Unknown Indication
Wellbutrin SR
Indication: Drug USE FOR Unknown Indication
Cymbalta
Indication: Drug USE FOR Unknown Indication
Neurontin
Indication: Drug USE FOR Unknown Indication
Viagra
Indication: Drug USE FOR Unknown Indication
Possible Lamictal side effects / adverse reactions in 66 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2010-03-05Patient: 66 year old female
Reactions: Bone Marrow Failure
Adverse event resulted in: death, life threatening event
Suspect drug(s):
Xanax
Dosage: 0.25 mg, once per day
Administration route: Oral
Temozolomide
Dosage: 250 mg, once per day
Administration route: Oral
Indication: Glioblastoma
Start date: 2009-01-05
End date: 2009-02-04
Cortancyl
Dosage: 40 mg, 1x/day
Administration route: Oral
Lamictal
Dosage: 50 mg, 2x/day
Administration route: Oral
Bactrim DS
Dosage: 1 df, 3x/day
Administration route: Oral
Indication: Prophylaxis
Eupantol
Administration route: Oral
Possible Lamictal side effects / adverse reactions in female
Reported by a health professional (non-physician/pharmacist) from France on 2010-03-05Patient: female
Reactions: Pyrexia, Fall, Transaminases Increased, Eosinophilia, Gamma-Glutamyltransferase Increased, Rash Maculo-Papular, Lymphocyte Count Decreased, Toxic Skin Eruption
Adverse event resulted in: hospitalization
Suspect drug(s):
Effexor
Administration route: Oral
End date: 2010-02-08
Seresta
Administration route: Oral
End date: 2010-02-05
Lamictal
Administration route: Oral
End date: 2010-02-05
Aricept
Administration route: Oral
End date: 2010-02-08
Possible Lamictal side effects / adverse reactions in female
Reported by a pharmacist from Japan on 2010-03-05Patient: female
Reactions: Overdose, Suicide Attempt
Suspect drug(s):
Lamictal
Dosage: 75mg twice per day
Administration route: Oral
Indication: Bipolar Disorder
Start date: 2009-06-26
Lamictal
Dosage: 845mg per day
Administration route: Oral
Other drugs received by patient: Rivotril; Desyrel; SG; Halcion; Depas; Seroquel
Possible Lamictal side effects / adverse reactions in 44 year old female
Reported by a physician from Switzerland on 2010-03-05Patient: 44 year old female
Reactions: Joint Swelling, Erythema, Lividity
Suspect drug(s):
Xanax
Dosage: unk
End date: 2003-04-25
Seropram
Dosage: unk
End date: 2003-04-25
Tegretol
Dosage: unk
End date: 2003-04-25
Lamictal
Dosage: unk
Start date: 2003-04-26
Possible Lamictal side effects / adverse reactions in 35 year old female
Reported by a consumer/non-health professional from United States on 2010-03-05Patient: 35 year old female
Reactions: Movement Disorder, Paranoia, Dyskinesia, Fear, Muscle Twitching, Incoherent, Speech Disorder, Dysphonia, Swelling, Musculoskeletal Stiffness
Adverse event resulted in: disablity
Suspect drug(s):
Lamictal
Other drugs received by patient: Invega; Ambien CR; Glucophage
